MovDisordV3, Main, Exploration, bibRecord, 000F84

Short Latency Afferent Inhibition in Parkinson's Disease Patients with Dementia

Identifieur interne : 000F84 ( Main/Exploration ); précédent : 000F83; suivant : 000F85

Short Latency Afferent Inhibition in Parkinson's Disease Patients with Dementia

Auteurs : Ozlem Celebi [Turquie] ; Ca Gbreve N Mesut Temucin [Turquie] ; Bulent Elibol [Turquie] ; Esen Saka [Turquie]

Source :

Movement disorders [ 0885-3185 ] ; 2012.

RBID : Pascal:12-0315947

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Démence d'Alzheimer, Pathologie du système nerveux, Homme, Neurophysiologie.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Alzheimer disease, Human, Nervous system diseases, Neurophysiology, Parkinson disease.

Abstract

Background: Cortical cholinergic deficiency occurs in Parkinson's disease (PD) and is more severe in PD dementia (PDD). Short-latency afferent inhibition (SAI) can be used as an in vivo test for the evaluation of the cholinergic circuit in the cerebral motor cortex. Methods: SAI and neuropsychological profile were studied in nondemented PD, PDD, Alzheimer's disease (AD) patients, and age-matched controls. Results: SAI was significantly impaired in AD cases (94.7 ± 6.2 versus 55.5 ± 4.0; P < 0.0001). In PD patients, it was not different from controls (61.4 ± 5.8 versus 55.5 ± 4.0; P = 0.412). PDD cases demonstrated a significant impairment in SAI (91.4 ± 5.2 versus 55.5 ± 4.0; P < 0.0001). A high correlation was found between SAI and Mini-Mental State Examination (r = -0.68; P < 0.0001). Conclusions: These findings add further evidence that differential cholinergic deficiency occurs in PD and PDD. SAI can be a neurophysiological correlate of PDD.

Affiliations:

Turquie

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000135
to stream PascalFrancis, to step Curation: 002B79
to stream PascalFrancis, to step Checkpoint: 000056
to stream Main, to step Merge: 001035
to stream Main, to step Curation: 000F84

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Short Latency Afferent Inhibition in Parkinson's Disease Patients with Dementia</title>
<author><name sortKey="Celebi, Ozlem" sort="Celebi, Ozlem" uniqKey="Celebi O" first="Ozlem" last="Celebi">Ozlem Celebi</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Temucin, Ca Gbreve N Mesut" sort="Temucin, Ca Gbreve N Mesut" uniqKey="Temucin C" first="Ca Gbreve N Mesut" last="Temucin">Ca Gbreve N Mesut Temucin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Elibol, Bulent" sort="Elibol, Bulent" uniqKey="Elibol B" first="Bulent" last="Elibol">Bulent Elibol</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Saka, Esen" sort="Saka, Esen" uniqKey="Saka E" first="Esen" last="Saka">Esen Saka</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">12-0315947</idno>
<date when="2012">2012</date>
<idno type="stanalyst">PASCAL 12-0315947 INIST</idno>
<idno type="RBID">Pascal:12-0315947</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000135</idno>
<idno type="wicri:Area/PascalFrancis/Curation">002B79</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000056</idno>
<idno type="wicri:doubleKey">0885-3185:2012:Celebi O:short:latency:afferent</idno>
<idno type="wicri:Area/Main/Merge">001035</idno>
<idno type="wicri:Area/Main/Curation">000F84</idno>
<idno type="wicri:Area/Main/Exploration">000F84</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Short Latency Afferent Inhibition in Parkinson's Disease Patients with Dementia</title>
<author><name sortKey="Celebi, Ozlem" sort="Celebi, Ozlem" uniqKey="Celebi O" first="Ozlem" last="Celebi">Ozlem Celebi</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Temucin, Ca Gbreve N Mesut" sort="Temucin, Ca Gbreve N Mesut" uniqKey="Temucin C" first="Ca Gbreve N Mesut" last="Temucin">Ca Gbreve N Mesut Temucin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Elibol, Bulent" sort="Elibol, Bulent" uniqKey="Elibol B" first="Bulent" last="Elibol">Bulent Elibol</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Saka, Esen" sort="Saka, Esen" uniqKey="Saka E" first="Esen" last="Saka">Esen Saka</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hacettepe University Faculty of Medicine</s1>
<s2>Ankara</s2>
<s3>TUR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alzheimer disease</term>
<term>Human</term>
<term>Nervous system diseases</term>
<term>Neurophysiology</term>
<term>Parkinson disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term>
<term>Démence d'Alzheimer</term>
<term>Pathologie du   système nerveux</term>
<term>Homme</term>
<term>Neurophysiologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background: Cortical cholinergic deficiency occurs in Parkinson's disease (PD) and is more severe in PD dementia (PDD). Short-latency afferent inhibition (SAI) can be used as an in vivo test for the evaluation of the cholinergic circuit in the cerebral motor cortex. Methods: SAI and neuropsychological profile were studied in nondemented PD, PDD, Alzheimer's disease (AD) patients, and age-matched controls. Results: SAI was significantly impaired in AD cases (94.7 ± 6.2 versus 55.5 ± 4.0; P < 0.0001). In PD patients, it was not different from controls (61.4 ± 5.8 versus 55.5 ± 4.0; P = 0.412). PDD cases demonstrated a significant impairment in SAI (91.4 ± 5.2 versus 55.5 ± 4.0; P < 0.0001). A high correlation was found between SAI and Mini-Mental State Examination (r = -0.68; P < 0.0001). Conclusions: These findings add further evidence that differential cholinergic deficiency occurs in PD and PDD. SAI can be a neurophysiological correlate of PDD.</div>
</front>
</TEI>
<affiliations><list><country><li>Turquie</li>
</country>
</list>
<tree><country name="Turquie"><noRegion><name sortKey="Celebi, Ozlem" sort="Celebi, Ozlem" uniqKey="Celebi O" first="Ozlem" last="Celebi">Ozlem Celebi</name>
</noRegion>
<name sortKey="Elibol, Bulent" sort="Elibol, Bulent" uniqKey="Elibol B" first="Bulent" last="Elibol">Bulent Elibol</name>
<name sortKey="Saka, Esen" sort="Saka, Esen" uniqKey="Saka E" first="Esen" last="Saka">Esen Saka</name>
<name sortKey="Temucin, Ca Gbreve N Mesut" sort="Temucin, Ca Gbreve N Mesut" uniqKey="Temucin C" first="Ca Gbreve N Mesut" last="Temucin">Ca Gbreve N Mesut Temucin</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F84 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000F84 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:12-0315947
   |texte=   Short Latency Afferent Inhibition in Parkinson's Disease Patients with Dementia
}}

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Short Latency Afferent Inhibition in Parkinson's Disease Patients with Dementia

Short Latency Afferent Inhibition in Parkinson's Disease Patients with Dementia

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri